Manfaat Kefir Dan Yoghurt Sebagai Prospek Masa Depan Bahan Baku Kosmetik Antiaging Dan Ramah Lingkungan

Authors

  • Firman Rezaldi STIKES TUJUH BELAS
  • Jihan Nabilla Stikes Tujuh Belas
  • Rina Nurmaulawati Stikes Bhakti Husada Mulia Madiun
  • Novi Ayuwardani Stikes Bhakti Husada Mulia Madiun
  • Erni Suminar Universitas Padjadjaran
  • Mohammad Zulkarnain Universitas Trinita
  • Chairul Anam Afgani Universitas Teknologi Sumbawa
  • Roni Gumilar Dinas Ketahanan Pangan Banten
  • Heny Sasmita Universitas Mathla’ul Anwar Banten
  • Ucu Wandi Somantri Universitas Mathla’ul Anwar Banten

Keywords:

Antiaging, Probiotik, Kefir, Kosmetik Alami, Yoghurt

Abstract

Penuaan kulit merupakan proses biologis kompleks yang melibatkan stres oksidatif, penurunan kolagen, peradangan kronis, dan peningkatan aktivitas enzim pemecah matriks seperti MMPs. Dalam upaya mencari bahan aktif alami yang efektif dan berkelanjutan untuk kosmetik anti-aging, produk fermentasi susu seperti kefir dan yoghurt mulai mendapat perhatian. Keduanya mengandung berbagai komponen bioaktif seperti probiotik, peptida, eksopolisakarida, asam organik, dan senyawa antioksidan yang dapat menurunkan stres oksidatif, meningkatkan sintesis kolagen, serta memperbaiki fungsi barrier kulit. Kajian literatur ini bertujuan menelaah mekanisme biologis kefir dan yoghurt dalam memperlambat penuaan kulit, mencakup aktivitas antioksidan, antiinflamasi, modulasi mikrobioma, dan stimulasi matriks dermis. Berdasarkan hasil telaah pustaka terbaru, kefir dan yoghurt terbukti berpotensi besar sebagai bahan aktif kosmetik anti-aging yang ramah lingkungan dengan keunggulan pada keberlanjutan proses fermentasi dan pemanfaatan limbah biomassa. Namun, dibutuhkan penelitian lanjut mengenai formulasi topikal terstandar dan uji klinis untuk memastikan efektivitas serta keamanan penggunaannya.

 

References

Ahmed, A. S., El-Bassiony, T., Elmalt, L. M., & Ibrahim, H. R. (2015). Identification of potent antioxidant bioactive peptides from goat milk proteins. Food Research International, 74, 80-88.

Alves, E., Gregório, J., Baby, A. R., Rijo, P., Rodrigues, L. M., & Rosado, C. (2021). Homemade kefir consumption improves skin condition—a study conducted in healthy and atopic volunteers. Foods, 10(11), 2794.

Alves, A. C., Martins Jr, S. M. D. S. B., Belo, J. V. T., Lemos, M. V. C., Lima, C. E. D. M. C., Silva, C. D. D., ... & Nascimento da Silva, L. C. (2024). Global trends and scientific impact of topical probiotics in dermatological treatment and skincare. Microorganisms, 12(10), 2010.

Alves, E., Gregório, J., Rijo, P., Rosado, C., & Rodrigues, L. M. (2022). The impact of kefir on epidermal water homeostasis in healthy human skin. Life, 12(7), 1075.

Apalowo, O. E., Adegoye, G. A., Mbogori, T., Kandiah, J., & Obuotor, T. M. (2024). Nutritional characteristics, health impact, and applications of kefir. Foods, 13(7), 1026.

Badilli, U., & Inal, O. (2025). Current approaches in cosmeceuticals: peptides, biotics and marine biopolymers. Polymers, 17(6), 798.

Canovai, A., & Williams, P. A. (2025). Pyrroloquinoline quinone: a potential neuroprotective compound for neurodegenerative diseases targeting metabolism. Neural Regeneration Research, 20(1), 41-53.

Chiani, F. (2025). Kefir and healthy aging: revealing thematic gaps through AI-assisted screening and semantic evidence mapping. Frontiers in Aging, 6, 1628474.

Da Anunciação, T. A., Guedes, J. D. S., Tavares, P. P. L. G., de Melo Borges, F. E., Ferreira, D. D., Costa, J. A. V., ... & Magalhães-Guedes, K. T. (2024). Biological significance of probiotic microorganisms from kefir and kombucha: a review. Microorganisms, 12(6), 1127.

Farag, M. A., Jomaa, S. A., Abd El-Wahed, A., & R. El-Seedi, H. (2020). The many faces of kefir fermented dairy products: quality characteristics, flavour chemistry, nutritional value, health benefits, and safety. Nutrients, 12(2), 346.

Feng, X., Shang, J., Gu, Z., Luo, X., Chen, Y., & Liu, Y. (2024). Lactic acid chemical peeling in skin disorders. Clinical, Cosmetic and Investigational Dermatology, 901-909.

Habeebuddin, M., Karnati, R. K., Shiroorkar, P. N., Nagaraja, S., Asdaq, S. M. B., Khalid Anwer, M., & Fattepur, S. (2022). Topical probiotics: more than a skin deep. Pharmaceutics, 14(3), 557.

He, X., Wan, F., Su, W., & Xie, W. (2023). Research progress on skin aging and active ingredients. Molecules, 28(14), 5556.

??tocha, A., Michalczyk, A., Bielecka, E., Kantyka, T., Miastkowska, M., & Sikora, E. (2025). Skin microbiome friendly topical formulations containing probiotic–loaded alginate microspheres: in vitro studies. Scientific Reports, 15(1), 34246.

Liu, R., & Sun, B. (2024). Lactic acid bacteria and aging: unraveling the interplay for healthy longevity. Aging and Disease, 15(4), 1487.

Li, Y., Zhang, Y., Dong, L., Li, Y., Liu, Y., Liu, Y., ... & Liu, L. (2024). Fermentation of Lactobacillus fermentum NB02 with feruloyl esterase production increases the phenolic compounds content and antioxidant properties of oat bran. Food Chemistry, 437, 137834.

Millman, J. F., Kondrashina, A., Walsh, C., Busca, K., Karawugodage, A., Park, J., ... & Lane, J. A. (2024). Biotics as novel therapeutics in targeting signs of skin ageing via the gut-skin axis. Ageing Research Reviews, 102, 102518.

Papadopoulou, D., Chrysikopoulou, V., Rampaouni, A., & Tsoupras, A. (2024). Antioxidant and anti-inflammatory properties of water kefir microbiota and its bioactive metabolites for health promoting bio-functional products and applications. AIMS microbiology, 10(4), 756.

Papadopoulou, D., Chrysikopoulou, V., Rampaouni, A., Plakidis, C., Ofrydopoulou, A., Shiels, K., ... & Tsoupras, A. (2025). Antioxidant, Antithrombotic and Anti-Inflammatory Properties of Amphiphilic Bioactives from Water Kefir Grains and Its Apple Pomace-Based Fermented Beverage. Antioxidants, 14(2), 164.

Piazzesi, A., Scanu, M., Ciprandi, G., & Putignani, L. (2024). Modulations of the skin microbiome in skin disorders: A narrative review from a wound care perspective. International Wound Journal, 21(10), e70087.

Pintea, A., Manea, A., Pintea, C., Vlad, R. A., Bîrsan, M., Antonoaea, P., ... & Ciurba, A. (2025). Peptides: Emerging candidates for the prevention and treatment of skin senescence: A review. Biomolecules, 15(1), 88.

Rezaldi, F., Millah, Z., Susiyanti, S., Gumilar, R., & Yenny, R. F. (2024). Peran Biotek Gen Tanaman Pada Bidang Pangan dan Farmasi Sebagai Bahan Sediaan Pangan Fungsional, Bahan Aktif Obat dan Kosmetik Natural. Jurnal Agroteknologi Merdeka Pasuruan, 8(1), 01-09.

Saleem, K., Ikram, A., Saeed, F., Afzaal, M., Ateeq, H., Hussain, M., ... & Asif Shah, M. (2023). Nutritional and functional properties of kefir. International Journal of Food Properties, 26(2), 3261-3274.

Tarracchini, C., Lordan, C., Milani, C., Moreira, L. P., Alabedallat, Q. M., de Moreno de LeBlanc, A., ... & Ventura, M. (2025). Vitamin biosynthesis in the gut: interplay between mammalian host and its resident microbiota. Microbiology and Molecular Biology Reviews, 89(2), e00184-23.

Yudianto, T., Pramono, E., Rezaldi, F., Rahmad, S. S., Yenny, R. F., Gumilar, R., ... & Suminar, E. (2025). Penguatan Konsep Berbasis Pertanian Berkelanjutan di Negara India sebagai Solusi Mengurangi Efek Gas Rumah Kaca (Literature Review). Jurnal Agroteknologi, 4(01), 46-66.

Zhang, Y., Liu, P., Fu, H., Wang, D., Zhao, D., Zhang, J., ... & Li, M. (2022). Effects of Lactobacillus kefiri fermentation supernatant on skin aging caused by oxidative stress. Journal of Functional Foods, 96, 105222.

Zolghadrpour, M. A., Jowshan, M. R., Seyedmahalleh, M. H., Imani, H., Karimpour, F., & Asghari, S. (2024). Consumption of a new developed synbiotic yogurt improves oxidative stress status in adults with metabolic syndrome: a randomized controlled clinical trial. Scientific Reports, 14(1), 20333.

Additional Files

Published

2025-11-01

Issue

Section

Articles